An Overview From The Researchers At Pretty Peptide

"Bremelanotide is a highly specialised melanocortin receptor agonist primarily investigated for its regulatory effects on the central nervous system. In strictly controlled in vitro and cellular models, researchers utilise this cyclic heptapeptide to observe its unique binding affinity to MC3R and MC4R pathways within the hypothalamus. By supplying this synthetic peptide for advanced laboratory research, we empower scientists to deeply investigate the fundamental mechanisms of neuromodulation, libido modulation, and central arousal signalling without introducing uncontrolled systemic variables." 

- Pretty Peptide Research Team

Reconstitution and Storage Guidelines

Proper handling and storage of PT-141 are critical for maintaining the structural integrity of the peptide for accurate in vitro testing.

Storage Instructions

• Unopened Vials: Store under refrigeration at 2°C to 8°C.
• Opened Vials: Store in a refrigerator and use until expiry date.

Frequently Asked Questions 

What is the primary mechanism of Pretty Peptide PT-141?

PT-141 works by activating the melanocortin receptors, specifically MC3R and MC4R, in the central nervous system. This allows researchers to study physiological responses that bypass the cardiovascular system.

Is PT-141 safe for human consumption?

This product is sold strictly for laboratory research and in vitro testing. It is not approved for human consumption, medical diagnosis, or therapeutic use. Always follow local regulatory guidelines regarding research peptides.

How do I verify the purity of my Pretty Peptide order?

Every batch of Pretty Peptide PT-141 undergoes rigorous HPLC and Mass Spectrometry testing. Researchers can request a third-party Certificate of Analysis (CoA) to verify batch purity by contacting our customer support team.

Important Notice

This product is provided by Pretty Peptide strictly for laboratory research purposes only. It is not intended for human use, medical use, or veterinary use. It should only be handled by qualified laboratory professionals.

Research Applications

Research applications for bremelanotide span various advanced fields of neurobiology, focusing on how central nervous system pathways respond to direct melanocortin stimulation.

• Melanocortin Activation: Scientists utilise this compound to observe how it binds directly to central nervous system pathways rather than acting on the vascular system.
• Libido Modulation: The peptide is extensively researched in cellular and animal models to map its role in modulating neurological pathways associated with sexual function.
• Energy and Focus: Laboratory professionals deploy PT-141 in studies to indicate its potential role in mood and behavioural motivation pathways.

Understanding the precise molecular characteristics of PT-141 is essential for ensuring accurate and reproducible data in rigorous scientific laboratory settings. The following specifications detail the foundational physical and chemical properties of our research-grade compound.

• Full Name: PT-141 / Bremelanotide
• Also Known As: Vyleesi (pharmaceutical), Melanotan II metabolite, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
• Structure: Cyclic heptapeptide — lactam bridge (Asp-Lys)
• Amino Acids: 7 (cyclic heptapeptide)
• Molecular Weight: 1,025.2 Da
• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• CAS Number: 189691-06-3
• MCR Potency Order: MC1R > MC4R > MC3R > MC5R > MC2R
• Primary Research Target: MC4R (medial preoptic area / paraventricular nucleus)
• Purity: >99% (HPLC verified)
• Form: Pre-mixed liquid peptide
• Storage: Store refrigerated at 2–8°C; protect from light